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Protein Targeting with Small Molecules:
Chemical Biology Techniques and Applications
New opportunities to use small molecules both as probes for
deciphering the control mechanism of living organisms and as
potential leads for developing new therapeutics for disease
treatment are ushering in a new era of chemical biology. Summarizing
the major issues and approaches to chemical biology and the
applications in drug design and development, Small
Molecules for Protein Targeting provides
chemical biologists and medicinal chemists with a detailed review of
chemical genomics, target profiling immobilization technology,
detection methods, and much more.
Chapter 7:
Development of small molecule ligands and inhibitors (Leonid
L. Chepelev, Nikolai L. Chepelev,
Hooman Shadnia,
William G. Willmore, James S. Wright, and Michel Dumontier). |
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